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Genetic testing

London Fertility Centre is one of the few clinics in the UK to offer a comprehensive genetic screening and diagnosis of embryos and sperm

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We offer a full range of genetic tests including pre-implantation genetic diagnosis (PGD), pre-implantation genetic screening (PGS), comparative genomic hybridization (Array CGH), sperm DNA fragmentation and sperm chromosome abnormality (aneuploidy) analysis.

Genetic testing may be recommended if you have a known genetic condition, if you have previously had failed fertility treatments or if you are a man who is considering trying for a baby after chemotherapy treatment.

Please call us on 020 7224 0707 or enquire online about any of our genetic testing.

PGD, PGS and Array CGH

PGD or PGS may be an option if you have a known genetic condition, have had recurrent miscarriages or recurrent implantation failure following IVF, or if you are having a baby in your late thirties or fourties as research shows older mothers have an increased chance of giving birth to babies with conditions like Down’s Syndrome.

Our results indicate that, for certain patients, PGS treatment has led to higher successful pregnancy rates.

We also provide comparative genomic hybridization (Array CGH), a new technique used alongside PGS which has significantly improved the accuracy of the procedure.

Do I need to meet any criteria to have my embryos genetically tested?

You need to be referred by one of our fertility doctors in order to have PGS or PGD. They will only refer if they believe you are suitable for the treatment, are aware of the advantages and disadvantages of embryo biopsy, have discussed the risks involved and the accuracy of results and have your consent for the procedure.

Sperm DNA fragmentation and sperm chromosome abnormality analysis

Sperm DNA fragmentation and sperm chromosome abnormality analysis tests provides information about sperm quality that is not always detected by a routine semen analysis.

Research indicates that live birth rates can be dramatically reduced if you have a high levels of sperm DNA fragmentation damage, and 20-30% of men who seek fertility treatment have abnormally high levels of sperm DNA fragmentation. This may compromise the possibility of a successful pregnancy no matter what fertility treatment is used, so by testing for it we can advise on lifestyle changes which may need to be made to improve the quality of your sperm before fertility treatment is carried out.

The sperm chromosome test can provide patients with important information that can help reduce the likelihood of repeated failed IVF cycles and miscarriage. It is estimated that one in five chromosomal abnormalities detected in embryos are the result of abnormalities derived from sperm. This is true even in cases where sperm morphology and count are normal.